Rex-1 (for reduced expression), also designated zinc finger protein 42 (ZFP42), is an acidic zinc finger protein.
Rex-1 contains four repeats of the zinc finger nucleic acid-binding motif and a potential acidic activator domain, suggesting that it is a regulatory protein.
Rex-1 localizes to the nucleus and is highly expressed in embryonic stem (ES) and undifferentiated murine F9 teratocarcinoma cells.
At the transcriptional level, expression of Rex-1 is reduced when F9 cells are induced to differentiate by the addition of retinoic acid (RA), and Rex-1 repression is enhanced by E1A.
The Oct-3/4 transcription factor can either activate or repress the Rex-1 promoter, depending on the cellular environment, while Oct-6 can lower the expression of Rex-1.
Applications:Suitable for use in ELISA, Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:200-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：20ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.3, 0.05% sodium azide, 50% glycerol.
Specificity：Recognizes human ZFP42.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to human ZFP42.
