SLC39A3 (solute carrier family 39, member 2), is a 314 amino acid acid multi-pass membrane protein that localizes to the cell membrane and belongs to the ZIP family of zinc transporters.
Two isoforms of ZIP3 exist as a result of alternative splicing events.
ZIP3 is involved in translocation of extracellular zinc into a variety of cell types.
Tumorigenic prostate epithelial cells contain less intracellular zinc than non-tumorigenic prostate epithelial cells.
Loss of the ability to maintain zinc accumulation may be caused by the decrease in the ZIP1 protein expression and the intracellular redistribution of ZIP3.
Applications:Suitable for use in ELISA, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry: 1:20-1:100 Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.3, 0.05% sodium azide, 50% glycerol.
Specificity：Recognizes human SLC39A3. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：E IHC
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to human SLC39A3.
