84-4649-63　［取扱停止］SLC17A1 200ul　394456

特徴

• NPT1, also called sodium-dependent phosphate transport protein, belongs to the organic anion transporter family, SLC17A.
• It is mainly expressed in the kidney transporting small organic anions such as PAH (para-aminohippurate), but it is also found in the liver and brain.
• NTP1 localizes to the apical membrane of renal proximal tubular cells and functions as a voltage driven organic anion/Cl-exchanger.
• It also plays a role in maintaining phosphate homeostasis.
• The expression of NPT1 is transcriptionally regulated by HNF-1å and HNF-3∫.
• Indomethacin and salicylate inhibit NPT1-mediated PAH transport.
• Applications:Suitable for use in ELISA, Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.