RNF43 (ring finger protein 43), also known as URCC or RNF124, is a 783aa single-pass type I membrane protein of the Endoplasmic reticulum and nuclear envelope that is thought to function as an E3 ubiquitin-protein ligase.
Containing one RING-type zinc finger and existing as four alternatively spliced isoforms, RNF43 is expressed in fetal kidney and lung, as well as in cancers of the lung, colon and kidney.
RNF43 functions as a cytotoxic T lymphocyte tumor antigen, and is therefore considered a target for cancer immunotherapy.
Applications:Suitable for use in ELISA, Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:200-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：20ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.3, 0.05% sodium azide, 50% glycerol.
Specificity：Recognizes human RNF43.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to human RNF43.
