RGS22 (regulator of G-protein signaling 22), also known as FLJ75004, PRTD-NY2, FLJ40080, MGC102908 or DKFZp434I092, is a novel 1264 amino acid regulator of G-protein signaling specific to to testis.
RGS22 inhibits signal transduction and contains two isoforms as a result of alternative splicing.
RGS22 is found in spermatogenic cells and Leydig cells, and may be involved in the translocation of GNA13 from the cytoplasm to the nucleus during spermiogenesis.
RGS22 contains two RGS domains: RGS1 and RGS2, and the gene encoding RGS22 maps to human chromosome 8q22.2.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:25-1:100Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.3, 0.05% sodium azide, 50% glycerol.
Specificity:Recognizes human RGS22.
Isotype:IgG
Calc Applications Abbrev:E IHC WB
Calc Crossreactivity:Hu
Immunogen:Recombinant protein corresponding to human RGS22.