This gene encodes a small GTP-binding protein that belongs to the largest family within the Ras superfamily.
Rab35 plays an important role in insulin-stimulated GLUT4 translocation in adipocytes.
It is the target of TBC1D10A–C and that the intracellular accumulation of endosomal vesicles and impairs exosome secretion were occured when inhibition of Rab35 function.
The surface of oligodendroglia in a GTP-dependent manner was localized Rab35, it increases the density of vesicles, and may have a function in docking or tethering.
Applications:Suitable for use in ELISA, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.3, 0.05% sodium azide, 50% glycerol.
Specificity：Recognizes human RAB35. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：E IHC
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to human RAB35.
