This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme.
Essential for T-cell receptor (TCR)-mediated T-cell activation, but is dispensable during TCR-dependent thymocyte development.
Links the TCR signaling complex to the activation of NF-kappa-B in mature T lymphocytes.
Required for interleukin-2 (IL2) production.
PKC is activated by diacylglycerol.
which in turn phosphorylates a range of cellular proteins.
PKC also serves as the receptor for phorbol esters, a class of tumor promoters.
Applications:Suitable for use in Western Blot, Immunofluorescence, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Immunohistochemistry: 1:50-1:100Immunofluorescence: 1:100-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.3, 0.05% sodium azide, 50% glycerol.
Specificity：Recognizes human PRKCQ. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：IF IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to human PRKCQ.
