84-4597-53　［取扱停止］MYD88 200ul　391876

特徴

• This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response.
• This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways.
• These pathways regulate that activation of numerous proinflammatory genes.
• The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain.
• Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections.
• Alternate splicing results in multiple transcript variants.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Immunohistochemistry: 1:25-1:100Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.