The protein encoded by this gene is a major non-neuronal microtubule-associated protein.
This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU).
This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion.
Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules.
The phosphorylation of this protein affects microtubule properties and cell cycle progression.
Multiple transcript variants encoding different isoforms have been found for this gene.
Applications:Suitable for use in ELISA, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry: 1:15-1:50Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：20ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.3, 0.05% sodium azide, 50% glycerol.
Specificity：Recognizes human MAP4.
Isotype：IgG
Calc Applications Abbrev：E IHC
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to human MAP4.
