Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering.
Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans.
Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells.
Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur.
Protects against human immunodeficiency virus-1 (HIV-1) infection.
Binds to high-mannose structures present on the envelope glycoprotein which is followed by subsequent targeting of the virus to the Birbeck granules leading to its rapid degradation.
Applications:Suitable for use in Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry: 1:50-1:100Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes human Langerin. Species Crossreactivity: mouse
Isotype：IgG
Calc Applications Abbrev：IHC
Calc Crossreactivity：Hu Mo
Immunogen：Recombinant protein corresponding to human C-type lectin domain family 4 member K.
