This gene encodes a member of the grandular kallikrein protein family.
Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19.
Members of this family are involved in a diverse array of biological functions.
The protein encoded by this gene is a highly active trypsin-like serine protease that selectively cleaves at arginine residues.
This protein is primarily expressed in prostatic tissue and is responsible for cleaving pro-prostate-specific antigen into its enzymatically active form.
This gene is highly expressed in prostate tumor cells and may be a prognostic maker for prostate cancer risk.
Alternate splicing results in both coding and non-coding transcript variants.
Applications:Suitable for use in ELISA, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:20ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.3, 0.05% sodium azide, 50% glycerol.
Specificity:Recognizes human KLK2.
Isotype:IgG
Calc Applications Abbrev:E IHC
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide corresponding to human KLK2.