84-4551-33　［取扱停止］Glucose Regulated Protein 75 (Grp75, HSPA9, heat shock 70kDa protein 9 (mortalin), CSA, HSPA9B, MGC4500, Mortalin, MOT, MOT2, mot-2, mthsp75, MTHSP75, PBP74, Peptide-binding protein 74, Stress-70 protein, mitochondrial) 200ul　389589

特徴

• Grp75, also known as mortalin, is a member of Hsp70 family of chaperone proteins that is not heat-inducible.
• This protein is essential for transporting many mitochondrial proteins from the cytoplasm to mitochondria.
• Grp75 inactivates the tumor suppressor p53.
• Studies found that Grp75 is overexpressed in many tumor tissues and immortalized human cell lines, suggesting its role in the tumor formation.
• Grp75 is also implicated in cell aging, as its overexpression appears to prolong the life span of human fibroblasts.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.