This gene is a member of the frizzled gene family.
Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins.
Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway.
The function of this protein is unknown, although it may play a role in mammalian hair follicle development.
Alternative splicing results in multiple transcript variants.
This gene is a susceptibility locus for schizophrenia.
Applications:Suitable for use in ELISA, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry: 1:25-1:100Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:20ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.3, 0.05% sodium azide, 50% glycerol.
Specificity:Recognizes human FZD3. Species Crossreactivity: mouse
Isotype:IgG
Calc Applications Abbrev:E IHC
Calc Crossreactivity:Hu Mo
Immunogen:Synthetic peptide corresponding to human FZD3.