FEM1A (FEM-1 homolog a), also known as EPRAP (Prostaglandin E receptor 4-associated protein), is a 669 amino acid cytoplasmic protein that belongs to the FEM-1 family.
FEM1A is present in atheromata and in macrophages derived from peripheral blood monocytes.
FEM1A may be a component of an E3 ubiquitin-protein ligase complex and functions as a substrate recognition subunit.
It is suggested that FEM1A participates in anti-inflammatory signaling of macrophages via its interaction with EP4.
FEM1A is down-regulated in Rhabdomyosarcoma, the most common soft tissue neoplasm of children.
FEM1A is considered a candidate gene for polycystic ovary syndrome.
Applications:Suitable for use in ELISA, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry: 1:25-1:100Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：20ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.3, 0.05% sodium azide, 50% glycerol.
Specificity：Recognizes human FEM1A.
Isotype：IgG
Calc Applications Abbrev：E IHC
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to human FEM1A.
