FAM13B is a 915 amino acid protein that is encoded by a gene that maps to human chromosome 5.
With 181 million base pairs encoding around 1,000 genes, chromosome 5 is about 6% of human genomic DNA.
It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene.
Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene.
Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome.
Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
Applications:Suitable for use in ELISA, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry: 1:25-1:100Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:20ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.3, 0.05% sodium azide, 50% glycerol.
Specificity:Recognizes human FAM13B. Species Crossreactivity: mouse
Isotype:IgG
Calc Applications Abbrev:E IHC
Calc Crossreactivity:Hu Mo
Immunogen:Synthetic peptide corresponding to human FAM13B.