ERP44 is a 406 amino acid protein that contains one thioredoxin domain, a motif that participates in various redox reactions throughout the cell.
Localized to the lumen of the endoplasmic reticulum (ER), TXNDC4 functions to inhibit the activity of IP3R-I (inositol 1,4,5-triphosphate receptor, type 1) within calcium channels.
In addition, TXNDC4 is thought to regulate oxidative protein folding within the ER and may be involved in retaining proteins.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:2000-5000Immunohistochemistry: 1:25-100Western Blot: 1:500-2000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.3, 0.05% sodium azide, 50% glycerol.
Specificity:Recognizes human ERP44. Species Crossreactivity: mouse
Isotype:IgG
Calc Applications Abbrev:E IHC WB
Calc Crossreactivity:Hu Mo
Immunogen:Synthetic peptide corresponding to human ERP44.