cdc25C is highly conserved during evolution and it plays a key role in the regulation of cell division.
The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family.
It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis.
It is also thought to suppress p53-induced growth arrest.
Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.
Applications:Suitable for use in Western Blot, Immunofluorescence, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Immunohistochemistry: 1:50-1:100Immunofluorescence: 1:100-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.3, 0.05% sodium azide, 50% glycerol.
Specificity：Recognizes human CDC25C.
Isotype：IgG
Calc Applications Abbrev：IF IHC WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to human CDC25C.
