Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors.
The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals.
A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity.
Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia.
Two alternative transcripts encoding different isoforms have been described.
Applications:Suitable for use in ELISA, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry: 1:25-1:100Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：20ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.3, 0.05% sodium azide, 50% glycerol.
Specificity：Recognizes human ARHGEF11. Species Crossreactivity: rat
Isotype：IgG
Calc Applications Abbrev：E IHC
Calc Crossreactivity：Hu Rt
Immunogen：Synthetic peptide corresponding to human ARHGEF11.
