UNC-51 like kinase 1 (ULK1) is widely expresed and contains an N-terminal kinase domain followed by a central proline-serine rich domain and a highly conserved C-terminal domain.
It has been linked to axon growth and is essential for autophagy.
Structurally, ULK1 is similar to ATG1, and it appears that both Atg1/ULK1 can bind to several ATG proteins regulating phosphorylation states and protein trafficking.
Applications:Suitable for use in Western Blot, Immunocytochemistry/Immunofluorescence.
Other applications not tested.
Recommended Dilution:Western Blot: 1:1000Immunocytochemistry/Immunofluorescence: 1:100Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by peptide affinity chromatography.
Form：Supplied as a liquid in PBS, 0.09% sodium azide, 50% glycerol.
Specificity：Recognizes human ULK1 at ~100kD. Species Crossreactivity: mouse, rat.
Isotype：IgG
Calc Applications Abbrev：IC IF WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to aa567-577 from mid of human ULK1.
Shelf Life：1year
Swiss Prot Number：O75385
EU Commodity Code：30021010
商品名：ULK1 (Unc-51 Like Kinase 1 (C. Elegans), Autophagy Related Protein 1 Homolog, Autophagy-Related Protein 1 Homolog, Serine/Threonine-Protein Kinase ULK1, Unc51.1, ATG1A, UNC51, C. Elegans, Homolog, EC:2.7.11.1, Serine/Threonine Protein Kinase Unc51.1, FLJ46475, ATG 1, hATG1, ATG1, Unc-51-Like Kinase 1, Serine/Threonine Protein Kinase ULK1, ULK1, Unc 51 Like Kinase 1, KIAA0722, UNC 51, ULK 1, ULK1 HUMAN, UNC51, Unc 51 (C. Elegans) Like Kinase 1, ATG1 Autophagy Related 1 Homolog) 100ug
