84-4459-45 ［取扱停止］SQSTM1 (EBI3-Associated Protein Of 60kD, ORCA, Osi, SQSTM 1, ZIP 3, A170, SQSTM1, Ubiquitin Binding Protein p62, Protein Kinase C-Zeta-Interacting Protein, FTDALS3, Ubiquitin-Binding Protein p62, PKC-Zeta-Interacting Protein, EBIAP, Sqstm1, Phosphotyrosine Independent Ligand For The Lck SH2 Domain Of 62kD, EBI3 Associated Protein p60, EBI3 Associated Protein Of 60kD, SQSTM HUMAN, OSF-6, Paget ... 384993
84-4459-45 ［取扱停止］SQSTM1 (EBI3-Associated Protein Of 60kD, ORCA, Osi, SQSTM 1, ZIP 3, A170, SQSTM1, Ubiquitin Binding Protein p62, Protein Kinase C-Zeta-Interacting Protein, FTDALS3, Ubiquitin-Binding Protein p62, PKC-Zeta-Interacting Protein, EBIAP, Sqstm1, Phosphotyrosine Independent Ligand For The Lck SH2 Domain Of 62kD, EBI3 Associated Protein p60, EBI3 Associated Protein Of 60kD, SQSTM HUMAN, OSF-6, Paget ... 384993
SQSTM1 or Sequestome 1 (p62) is a ubiquitin binding protein that interacts with ubiqutin, providing a scaffold for several signaling proteins and triggering degradation of proteins throught the proteasome or lysossome.
This gene regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway.
The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals.
Mutations in this gene result in sporadic and familial Paget disease of bone.
SQSTM1 also binds autophagosomal membrane protein LC3/ATG8.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.09% sodium azide, 50% glycerol.
Specificity：Recognizes human SQSTM1 at ~60kD. Band at 40kD is isoform 2. Species Crossreactivity: mouse.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo
Immunogen：Synthetic peptide corresponding to aa335-345 of human SQSTM1, at C-terminal.
Shelf Life：1year
Swiss Prot Number：Q13501
EU Commodity Code：30021010
商品名：SQSTM1 (EBI3-Associated Protein Of 60kD, ORCA, Osi, SQSTM 1, ZIP 3, A170, SQSTM1, Ubiquitin Binding Protein p62, Protein Kinase C-Zeta-Interacting Protein, FTDALS3, Ubiquitin-Binding Protein p62, PKC-Zeta-Interacting Protein, EBIAP, Sqstm1, Phosphotyrosine Independent Ligand For The Lck SH2 Domain Of 62kD, EBI3 Associated Protein p60, EBI3 Associated Protein Of 60kD, SQSTM HUMAN, OSF-6, Paget Disease Of Bone 3, p62B, p60, PDB 3, EBI 3 Associated Protein p60, MGC127197, Phosphotyrosine-Independent Ligand For The Lck SH2 Domain Of 62kD, EBI 3 Associated Protein Of 60kD, ZIP3, STAP, p62, Sequestosome 1, OSIL, STONE14, Phosphotyrosine Independent Ligand For The Lck SH2 Domain p62, PDB3, Oxidative Stress Induced Like, Sequestosome-1, ZIP) 100ug
