Tumor necrosis factor ligand superfamily member 14 is a protein that in humans is encoded by the TNFSF14 gene.
TNFSF14 has also been designated as CD258, as well as LIGHT.
It was mapped on chromosome 19p13.3.
The protein encoded by this gene is a member of the tumor necrosis factor(TNF) ligand family.
This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus.
It has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells.
This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte.
Two alternatively spliced transcript variant encoding distinct isoforms have been reported.
Applications:Suitable for use in ELISA, Western Blot.
Other applications not tested.
Recommended Dilution:ELISA: 0.1-0.5ug/mlWestern Blot: 0.1-0.5ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months after receipt at -20°C.
Reconstitute with sterile dH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ug
Host：rabbit
Source Antibody：mouse
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder in 5mg/ml BSA, 0.9mg sodium chloride, 0.2mg Na2HPO4, 0.05% sodium azide. Reconstitute with 200ul sterile ddH2O to ~0.5mg/ml.
Specificity：Recognizes mouse LIGHT. Species Crossreactivity: rat
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Mo Rt
Immunogen：Recombinant protein corresponding to mouse LIGHT (Position: L59-V239), expressed in E. coli.
