84-4457-14　KCNH1 100ug　377469

特徴

• Potassium voltage-gated channel subfamily H member 1 is a protein that in humans is encoded by the KCNH1 gene.
• Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints.
• Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume.
• This gene encodes a member of the potassium channel, voltage-gated, subfamily H.
• This member is a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel.
• It is activated at the onset of myoblast differentiation.
• The gene is highly expressed in brain and in myoblasts.
• Overexpression of the gene may confer a growth advantage to cancer cells and favor tumor cell proliferation.
• Alternative splicing of this gene results in two transcript variants encoding distinct isoforms.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 0.1-0.5ug/mlOptimal dilutions to be determined by the researcher.
• Storage and Stability:Lyophilized powder may be stored at -20°C.
• Stable for 12 months after receipt at -20°C.
• Reconstitute with sterile dH2O.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Reconstituted product is stable for 12 months at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.