Segment polarity protein dishevelled homolog DVL-2 is a protein that in humans is encoded by the DVL2 gene.
This gene encodes a member of the dishevelled (dsh) protein family.
The vertebrate dsh proteins have ~40% amino acid sequence similarity with Drosophila dsh.
This gene encodes a 90kD protein that undergoes posttranslational phosphorylation to form a 95kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins.
The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 0.1-0.5ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months after receipt at -20°C.
Reconstitute with sterile dH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder in 5mg/ml BSA, 0.9mg sodium chloride, 0.2mg Na2HPO4, 0.05% sodium azide. Reconstitute with 200ul sterile ddH2O to ~0.5mg/ml.
Specificity：Recognizes human Dishevelled 2. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Synthetic peptide corresponding to aa35-64, AERITLGDFKSVLQRPAGAKYFFKSMDQD from human Dishevelled 2 at N-terminal. Species sequence homology: mouse and rat
