84-4454-39　SYN1, CT (Synapsin-1) 100ug　371043

特徴

• Synapsin I, is the collective name for Synapsin Ia and Synapsin Ib, two nearly identical phosphoproteins that in humans are encoded by the SYN1 gene.
• This gene is a member of the synapsin gene family.
• Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles.
• Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases.
• This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis.
• The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal.
• Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome.
• Alternatively spliced transcript variants encoding different isoforms have been identified.
• Applications: Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 0.1-0.5ug/mlImmunohistochemistry (paraffin): 0.5-1ug/mlOptimal dilutions to be determined by the researcher.
• Storage and Stability:Lyophilized powder may be stored at -20°C.
• Stable for 12 months after receipt at -20°C.
• Reconstitute with sterile ddH2O.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Reconstituted product is stable for 12 months at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.