84-4452-93　AKR1C1/C2 (Aldo-keto Reductase Family 1 Member C1/C2) 100ug　370899

特徴

• This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins.
• These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors.
• The enzymes display overlapping but distinct substrate specificity.
• This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity.
• And this gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
• Three transcript variants encoding two different isoforms have been found for this gene.
• Applications: Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 0.1-0.5ug/mlOptimal dilutions to be determined by the researcher.
• Storage and Stability:Lyophilized powder may be stored at -20°C.
• Stable for 12 months after receipt at -20°C.
• Reconstitute with sterile ddH2O.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Reconstituted product is stable for 12 months at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.