Ras homologue enriched in brain (Rheb) is a 17kD G-protein and evolutionarily conserved Ras family member, widely expressed in tissues other than the brain.
Compared with many small GTPases, Rheb is unique since it exists in a highly activated state in mammalian cells.
Rheb also plays an important part in regulating the TOR signally pathway.
Although Rheb is expressed at relatively high levels in the adult cortex, it can be rapidly induced in brain neurons by synaptic activity.
Following a seizure, it is transiently induced in the hippocampus.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1-2ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4°C in the dark.
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: APC conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2. Labeled with Allophycocyanin (APC).
Specificity：Recognizes human Rheb. Species Crossreactivity: rat, mouse
Isotype：IgG
Immunogen：Synthetic peptide corresponding to 15aa at the internal region of human Rheb.
