Twist transcription factor is a basic-helix-loop-helix transcription factor associated with Saethre-Chotzen syndrome.Basic helix-loop-helix (bHLH) transcription factors have been implicated in cell lineage determination and differentiation.
The protein encoded by this gene is a bHLH transcription factor and shares similarity with another bHLH transcription factor, Dermo1.
In the embryo, highly expressed in chondrogenic cells.
In embryonic skin, expressed in the undifferentiated mesenchymal layer beneath the epidermis which later develops into the dermis.
Expressed in early myeloid cells but not in lymphoid cells in the liver.
Expression also detected in the secretory ependymal epithelium of the choroid plexus primordium.
In the adult, expressed in secreting glandular tissues and tubules.
Applications: Suitable for use in ELISA, Western Blot, Immunoprecipitation, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
