Transcription factor SOX-18 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate.
The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins.
This protein plays a role in hair, blood vessel, and lymphatic vessel development.
Greenfield et al.
(1996) described a novel member of the mouse Sox gene family, Sox18, which is transcribed in adult lung and in cardiac and skeletal muscle.
They reported that the Sox18 protein binds the sequence AACAAAG in vitro and that it is capable of transactivating gene expression.
Pennisi et al.
(2000) found that Sox18 is expressed in the developing vascular endothelium and hair follicles in mouse embryos.
Applications: Suitable for use in ELISA, Western Blot, Immunoprecipitation, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
