Amino acid transporters play essential roles in the uptake of nutrients, production of energy, chemical metabolism, detoxification, and neurotransmitter cycling.
SLC38A1 is an important transporter of glutamine, an intermediate in the detoxification of ammonia and the production of urea.
Glutamine serves as a precursor for the synaptic transmitter, glutamate.The deduced 487aa protein is predicted to have a cytoplasmic N-terminal followed by 11 putative transmembrane domains and an extracellular C-terminal.
ATA1 has 2 N-glycosylation sites in the putative extracellular loop between transmembrane domains 5 and 6, and several protein kinase C phosphorylation sites.
ATA1 shares 93% identity with rat Ata1 and 52% identity with human ATA2 (SLC38A2).
Applications: Suitable for use in ELISA, Western Blot, Immunoprecipitation, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
