PLP2 encodes an integral membrane protein that localizes to the endoplasmic reticulum in colonic epithelial cells.
The encoded protein can multimerize and may function as an ion channel.
A polymorphism in the promoter of this gene may be linked to an increased risk of X-linked mental retardation.
A pseudogene of this gene is found on chromosome 5.
Oliva et al.
(1993) cloned a cDNA encoding the A4 differentiation-dependent protein from a human colon cell line.
Fisher et al.
(1997) identified the promoter and complete coding sequence of the A4 gene, which is organized into 5 exons spanning approximately 3.5kb of DNA.
The product of this gene is an integral membrane protein, containing 4 putative transmembrane domains that may play a role in cell differentiation in the intestinal epithelium.
Applications: Suitable for use in ELISA, Western Blot, Immunoprecipitation, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
