Obestatin is a putative hormone that is potentially produced in the cells lining the stomach and small intestine of several mammals including humans.
Research carried out at the Stanford University School of Medicine in 2005 identified the new hormone with a bioinformatics approach by computer search of the sequenced genomes of several organisms.
Obestatin is a putative peptide hormone - a relatively small protein.
It is encoded by the same gene that also encodes ghrelin, a peptide hormone that increases appetite.
The protein produced by that gene breaks into two smaller peptides, ghrelin and obestatin.
The purpose of this mechanism remains unclear, however it explains earlier findings, namely that removing the ghrelin gene from mice did not significantly reduce their appetite.
Obestatin has been shown to suppress appetite, thus opposing the action of ghrelin.
Applications: Suitable for use in ELISA, Western Blot, Immunoprecipitation, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
