Myelin transcription factor 1 is a member of a family of neural specific, zinc finger-containing DNA-binding proteins.
The protein binds to the promoter regions of proteolipid proteins of the central nervous system and plays a role in the developing nervous system.
Binds to the promoter regions of proteolipid proteins of the central nervous system.
May play a role in the development of neurons and oligodendrogalia in the CNS.
May regulate a critical transition point in oligodendrocyte lineage development by modulating oligodendrocyte progenitor proliferation relative to terminal differentiation and up-regulation of myelin gene transcription.
Expressed in neural progenitors and oligodendrocyte lineage cells.
More highly expressed in oligodendrocyte progenitors than in differentiated oligodendrocytes.
Applications: Suitable for use in ELISA, Western Blot, Immunoprecipitation, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.