84-4447-62　［受注停止］LRP1B (Low Density Lipoprotein Receptor Related Protein 1B, LRPDIT, LRP-DIT (Deleted In Tumors), Low-density Lipoprotein Receptor-related Protein-deleted in Tumor) 200ul　369563

特徴

• LRP1B belongs to the low density lipoprotein (LDL) receptor gene family.
• full-length LRP1B was unstable following transfection in Lrp1 null Chinese hamster ovary (CHO) cells.
• In order to characterize the ligands for LRP1B, generated a minireceptor of LRP1B that could be stably expressed in CHO cells.
• The minireceptor began with the EGF precursor-like repeat before the fourth cluster of ligand-binding repeats (domain IV) and contained ligand-binding domain IV, the transmembrane domain, and the cytoplasmic tail.
• Ligands for the minireceptor, including receptor-associated protein , urokinase plasminogen activator, tissue-type plasminogen activator , and plasminogen activator inhibitor-1, were bound, internalized, and degraded via their association with the minireceptor.
• Applications: Suitable for use in ELISA, Western Blot, Immunoprecipitation, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 0.05-2ug/mlWestern Blot: 0.05-2ug/mlImmunohistochemistry (frozen): 5-20ug/mlImmunohistochemistry (paraffin): 5-20ug/mlImmunocytochemistry: 5-20ug/mlOptimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.