Lipase Maturation Factor 2(LMF2) belongs to the lipase maturation factor family.Involved in the maturation of specific proteins in the endoplasmic reticulum.
May be required for maturation and transport of active lipoprotein lipase (LPL) through the secretory pathway.
The disorder is caused by a decrease in the activity of lipoprotein lipase (LPL) and the related enzyme hepatic lipase, caused by impaired maturation of nascent LPL and hepatic lipase polypeptides in the endoplasmic reticulum (Briquet-Laugier et al., 1999).
Peterfy et al.
(2007) identified the gene containing the cld mutation as Tmem112 and renamed it Lmf1 for 'lipase maturation factor-1.' They identified the mutation as a murine endogenous retrovirus (MuERV) insertion in intron 7 resulting in truncation of the protein.
Applications: Suitable for use in ELISA, Western Blot, Immunoprecipitation, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
