Lipase member H is a membrane-bound member of the mammalian triglyceride lipase family.
It catalyzes the production of 2-acyl lysophosphatidic acid (LPA), which is a lipid mediator with diverse biological properties that include platelet aggregation, smooth muscle contraction, and stimulation of cell proliferation and motility.Present in intestine (at protein level).
Expressed in colon, prostate, kidney, pancreas, ovary, testis, intestine, lung and pancreas.
Expressed at lower level in brain, spleen and heart.
In hair, it is prominently expressed in hair follicles, including the stem cell-rich bulge region.
Defects in LIPH are the cause of alopecia universalis congenita Mari type (AUCM).
AUCM is a recessive autosomal form of alopecia that is common in the Mari population, a large aboriginal Finno-Ugric population in the Volga-Ural region of Russia.
Applications: Suitable for use in ELISA, Western Blot, Immunoprecipitation, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
