EOMES encodes a member of a conserved protein family that shares a common DNA-binding domain, the T-box.
T-box genes encode transcription factors involved in the regulation of developmental processes.
A similiar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation.
Mutations in the mouse T (Brachyury) gene cause defects in mesoderm formation.
Several related genes, members of the T-box gene family, encode a similar N-terminal DNA-binding domain, the T-box, and play critical roles in human embryonic development.
Mutations in human TBX5 and TBX3, for example, cause the developmental disorders Holt-Oram syndrome and ulnar-mammary syndrome, respectively.
Applications: Suitable for use in ELISA, Western Blot, Immunoprecipitation, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-1:5000 Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
