CD52 is a protein present on the surface of mature lymphocytes.
It also is found in monocytes and dendritic cells.
It is a glycosylphosphatidylinositol (GPI)--anchored antigen expressed on the all lymphocytes as well as within the male genital tract.
The CAMPATH-1 family of monoclonal antibodies recognize an antigen expressed on human lymphocytes and monocytes.
The antigen is an unusually good target for complement-mediated attack and, for this reason, the IgM CAMPATH-1M, has been widely used for removal of T lymphocytes from donor bone marrow to prevent graft-vs-host disease.
Because the target antigen is expressed in most cases of lymphoid malignancy, serotherapy of lymphoma and leukemia with CAMPATH-1 has also been attempted.
Applications: Suitable for use in ELISA, Western Blot, Immunoprecipitation, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.