Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0).
Aquaporin 8 mRNA is found in pancreas and colon but not other tissues.
The human AQP8 protein is 40.4% identical to the plant water channel gamma-TIP, 76.0% identical to mouse Aqp8, 74.9% identical to rat Aqp8, 29.5% identical to human AQP2, and 28.9% identical to human AQP3.
Northern blot analysis of human tissues detected a 1.35-kb AQP8 mRNA only in pancreas and colon.
Like the genes of non-water-selective aquaporins, the AQP8 gene contains 6 exons; however, its exon-intron boundaries are different from the boundaries of those other aquaporin genes.
Applications: Suitable for use in ELISA, Western Blot, Immunoprecipitation, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-1:5000 Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
