ZNRD1 encodes a protein with similarity to the Saccharomyces cerevisiae Rpa12p subunit of RNA polymerase I.
Alternate splicing of this gene results in two transcript variants encoding the same protein.
Additional splice variants have been described, but their full-length sequences have not been determined.
Lepourcelet et al.
(1996) identified ZNRD1, which they called HTEX6, as 1 of several genes in the HLA-A /HLA-F region of chromosome 6.
The deduced protein contains 2 potential zinc-binding motifs and shows significant homology with the A12.2 subunit of yeast polymerase I and mouse Tctex6.
Coriton et al.
(2000) cloned ZNRD1 from a testis cDNA library.
The deduced protein contains 126 amino acids.
They also identified splice variants predicted to encode shorter peptides.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes human ZNRD1.
Isotype：IgG
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to Met1-Ser126 of human ZNRD1, fused to two N-terminal Tags, His-Tag and T7-tag, expressed in E. coli.
