VEGF-A is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis.
Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized
VEGF is a chemical signal produced by cells that stimulates the growth of new blood vessels.
The most important member is VEGF-A.
Other members are Placenta growth factor (PlGF), VEGF-B, VEGF-C and VEGF-D.
The latter ones were discovered later than VEGF-A, and, before their discovery, VEGF-A was called just VEGF.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-5000Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.