CXCL17 is a small cytokine belonging to the CXC chemokine family that has been identified in humans and mice.
CXCL17 attracts dendritic cells and monocytes and is regulated in tumors.
It is also known as VEGF co-regulated chemokine 1 (VCC-1) and dendritic cell- and monocyte-attracting chemokine-like protein (DMC)
This chemokine is constitutively expressed in the lung.
The predicted 119aa protein has a calculated molecular mass of 13.8kD and shares 71% identity with its mouse homolog.
DMC has an N-terminal signal peptide, but no N-glycosylation sites.
Secondary structure analysis showed highest similarity to CXCL8 (IL8), whereas circular dichroism analysis revealed that active, purified DMC adopted a secondary structure resembling that of CCL5 and CCL4.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-5000Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：rat
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes rat VCC1.
Isotype：IgG
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Rt
Immunogen：Recombinant protein corresponding to Ser23-Leu119 of rat VCC1 fused to His-Tag and GST-tag at N-terminal expressed in E. coli.
