Protein UXT is a novel protein which is highly conserved in mouse.
It interacts with the N-terminus of the androgen receptor and plays a role in facilitating receptor-induced transcriptional activation.
It is also likely to be involved in tumorigenesis as it is abundantly expressed in tumor tissues.
This gene is part of a gene cluster on chromosome Xp11.23.
Alternative splicing results in 2 transcript variants encoding different isoforms.
Based on a consensus sequence from 14 different ESTs with significant sequence similarity to UXT, they determined that UXT encodes a 157aa protein with 3 potential phosphorylation sites.
a protein that shares 90% identity with human UXT, with all 3 potential phosphorylation sites conserved, indicating that these sites are of functional importance.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes human UXT.
Isotype：IgG
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to Glu15-His157 of human UXT, fused to two N-terminal Tags, His-Tag and T7-tag, expressed in E. coli.
