84-4441-18　UBE2A (Ubiquitin Protein Ligase E3A, ANCR, AS, E6-AP, EPVE6AP, HPVE6A, Papilloma Virus E6-Associated,Angelman Syndrome, Oncogenic protein-associated protein E6-AP, Renal carcinoma antigen NY-REN-54) 200ul　365500

特徴

• Ubiquitin-protein ligase E3A (UBE3A) is an enzyme that in humans is encoded by the UBE3A gene.
• This enzyme is involved in targeting proteins for degradation within cells.
• Protein degradation is a normal process that removes damaged or unnecessary proteins and helps maintain the normal functions of cells.
• Ubiquitin protein ligase 3A attaches a small protein called ubiquitin to proteins that should be degraded.
• Cellular structures called proteasomes recognize and digest proteins tagged with ubiquitin.
• Both copies of the UBE3A gene are active in most of the body's tissues.
• In the brain, however, only the copy inherited from a person's mother (the maternal copy) is normally active.
• The UBE3A gene is located on the long (q) arm of chromosome 15 between positions 11 and 13, from base pair 23,133,488 to base pair 23,235,220.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400 Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.