84-4440-83　TSTA3 (Tissue Specific Transplantation Antigen P35B, FX, P35B, SDR4E1,Short-chain dehydrogenase/reductase family 4E member 1,GDP-L-Fucose Synthase, GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase) 200ul　365466

特徴

• Tissue specific transplantation antigen P35B is a NADP(H)-binding protein.
• It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose.
• GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens.
• Mutations in this gene may cause leukocyte adhesion deficiency, type II.
• Two step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.