84-4440-63　［受注停止］TRPA1 (Transient Receptor Potential Cation Channel Subfamily A, Member 1, ANKTM1, Ankyrin-like with transmembrane domains protein 1,Transformation-sensitive protein p120) 200ul　365446

特徴

• TRPA1 is a member of the transient receptor potential channel family.
• TRPA1, contains 14 N-terminal ankyrin repeats and is believed to function as a mechanical stress sensor.
• The specific function of this protein has not yet been determined; however, studies indicate the function may involve a role in signal transduction and growth control.
• Recent studies indicate that TRPA1 is activated by a number reactive compounds (allyl isothiocyanate, cinnamaldehyde, farnesyl thiosalicylic acid, Nicotine and its structural analogues formalin, hydrogen peroxide, 4-hydroxynonenal, and acrolein) and considered as a 'chemosensor' in the body.
• TRPA1 is considered as an attractive pain target based on the fact that TRPA1 knockout mice showed near complete attenuation of formalin-induced pain behaviors.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.