84-4440-42 TR (Tomoregulin, TMEFF2, TENB2, HPP1, TPEF, CT120.2, Transmembrane Protein With EGF-Like And Two Follistatin-Like Domains 2, Hyperplastic polyposis protein 1) 200ul 365425
84-4440-42 TR (Tomoregulin, TMEFF2, TENB2, HPP1, TPEF, CT120.2, Transmembrane Protein With EGF-Like And Two Follistatin-Like Domains 2, Hyperplastic polyposis protein 1) 200ul 365425
The deduced 368aa TRa protein contains 2 follistatin-like domains and a conserved EGF-like domain.
It also has a predicted N-terminal signal peptide, a transmembrane domain, a cytosolic tail G protein-activating motif, and potential sites for N-linked glycosylation and glycosaminoglycan attachment.
Unlike other EGF/NRG family members, TRa has a histidine replacing a conserved arginine essential for EGF receptor recognition.
The TRb and TRc proteins contain 418 and 379aa, respectively, and differ from one another and TRa in the cytoplasmic domain.
Northern blot analysis detected expression of approximately 2.2- and 3.1-kb TR transcripts predominantly in brain.
The 374aa TMEFF2 protein shares approximately 36% and 99% sequence identity with TMEFF1 and mouse Tmeff2, respectively.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity:Recognizes human TR.
Isotype:IgG
Calc Applications Abbrev:E IC IHC WB
Calc Crossreactivity:Hu
Immunogen:Recombinant protein corresponding to Thr52-Arg290 of human TR, fused to two N-terminal Tags, His-Tag and T7-tag, expressed in E. coli.