84-4439-89　［受注停止］TNFSF9 (Tumor Necrosis Factor Ligand Superfamily, Member 9, 4-1BB-L, Receptor 4-1BB Ligand, Homolog Of Mouse 4-1BB-L) 200ul　365373

特徴

• TNFSF9 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family.
• This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes.
• This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells.
• The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation.
• The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation.
• This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells.
• This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.