84-4439-71　TNFb (Tumor Necrosis Factor Beta, LT, LTA, TNF-B, TNFSF1, Tumor Necrosis Factor Ligand Superfamily Member 1, Lymphotoxin Alpha) 200ul　365355

特徴

• TNF-beta is a potent mediator of inflammatory and immune responses.TNF-beta is produced by activated T and B lymphocytes, and has similar activities to TNF-alpha.
• Like TNF-alpha, TNF-beta is involved in the regulation of various biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, coagulation, and neurotransmission.
• TNF-beta is secreted as a soluble polypeptide, but can form heterotrimers with lymphotoxin-beta, which effectively anchors the TNF-beta to the cell surface.
• TNF-beta is cytotoxic to a wide range of tumor cells.
• LTA is highly inducible, secreted, and exists as homotrimeric molecule.
• LTA forms heterotrimers with lymphotoxin-beta which anchors lymphotoxin-alpha to the cell surface.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
• AA Sequence:MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- KHLARGTL KPAAHLVGDP STPDSLRWRA NTDRAFLRHG FLLSNNSLLV PTSGLYFVYS QVVFSGEGCF PKATPTPLYL AHEVQLFSSQ YPFHVPLLSA QKSVCPGPQG PWVRSVYQGA VF
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.