84-4438-17　［受注停止］STMN1 (Stathmin 1, LAP18, C1orf215, Lag, OP18, PP17, PP19, PR22, SMN, Metablastin, Prosolin, Oncoprotein 18, Leukemia-associated phosphoprotein p18) 200ul　365201

特徴

• Stathmin 1/oncoprotein 18, also known as STMN1, is a highly conserved 17kD protein.
• Its function as an important regulatory protein of microtubule dynamics has been well characterized.
• Eukaryotic microtubules are one of three major components of the cell’s cytoskeleton.
• They are highly dynamic structures that continuously alternate between assembly and disassembly.
• Stathmin performs an important function in regulating rapid microtubule remodeling of the cytoskeleton in response to the cell’s needs.
• Microtubules are cylindrical polymers of alpha,Beta-tubulin.
• Their assembly is in part determined by the concentration of free tubulin in the cytoplasm.
• At low concentrations of free tubulin, the growth rate at the microtubule ends is slowed and results in an increased rate of depolymerization (disassembly).
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-1:5000 Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500 Immunohistochemistry (paraffin): 1:10-100 Immunocytochemistry: 1:50-500 Optimal dilutions to be determined by the researcher.
• AA Sequence:MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGS- ASSDIQVKE LEKRASGQAF ELILSPRSKE SVPEFPLSPP KKKDLSLEEI QKKLEAAEER RKSHEAEVLK QLAEKREHEK EVLQKAIEEN NNFSKMAEEK LTHKMEANKE NREAQMAAKL ERLREKDKHI EEVRKNKESK DPADETEAD
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.