Signal recognition particle (SRP) receptor also called docking protein, is a dimer composed of 2 different subunits that are associated exclusively with the rough ER in mammalian cells.
Its main function is to identify the SRP units.
SRP (signal recognition particle) is a molecule that helps the ribosome-mRNA-polypeptide complexes to settle down on the membrane of the endoplasmic reticulum.
Signal recognition particle receptor subunit beta is a protein has similarity to mouse protein which is a subunit of the signal recognition particle receptor (SR).
This subunit is a transmembrane GTPase belonging to the GTPase superfamily.
It anchors alpha subunit, a peripheral membrane GTPase, to the ER membrane.
SR is required for the cotranslational targeting of both secretory and membrane proteins to the ER membrane.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:100-1:5000Western Blot: 1:50-400Immunohistochemistry (frozen): 1:50-500Immunohistochemistry (paraffin): 1:10-100Immunocytochemistry: 1:50-500Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：mouse
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes mouse SRPRB.
Isotype：IgG
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Mo
Immunogen：Recombinant protein corresponding to Trp56-Ala269 of mouse SRPRB, fused to two N-terminal Tags, His-Tag and T7-tag, expressed in E. coli.
